首页 >> 导师简介 >> 病原生物学系 >> 正文
 
病原生物学系
刘超红


刘超红,华中科技大学基础医学院病原生物学系教授,副主任。国家自然科学基金优秀青年基金获得者。分别于武汉大学获理学学士学位,中科院武汉病毒所获硕士学位,美国马里兰大学帕克分校获博士学位,美国圣裘德儿童研究医院获博士后培训。现在主要研究领域是血液系统免疫相关疾病,包括免疫缺陷病和自身免疫疾病和白血病。研究方向包括免疫系统相关疾病和白血病中B细胞、iNKT细胞和调节性T细胞功能紊乱的分子机制。以第一作者或通讯作者发表12篇SCI文章,共同作者累积20篇文章。其工作在Plos Biology,Blood, Journal of Experimental Medicine, Cell report 和Journal of Immunology等杂志发表。任亚太医学生物免疫学会基础免疫学分会副秘书长,Journal of Clinical and Translational Hepatology编委。担任Scientific Report, Plos One 和Archive of Virology审稿人.

联系方式:chaohongliu80@126.com

 

 

 

 

发表文章

Bing Zheng1,2, Zhijiang Xi1,2, Rong Liu1,2, Wei Yin3, Zhiwei Sui4, Boxu Ren1,2, Heather Miller5, Quan Gong1,2*, Chaohong Liu6*.The function of microRNAs in B cell development, lymphoma, and their potential in clinical practice. Front Immunol. 2018 Apr 30;9:936. IF=6.429

 

Xiaoyu Sun 1,2,3,4§, Jinzhi Wang 1,2,3,4§, Tao Qin1,2,3,4, Yongjie Zhang5, Lu Huang1,2,3,4, Linlin Niu1,2,3,4, Xiaoming Bai6, Yukai Jing7, Xingtian Xuan1,2,3,4, Heather Miller8, Yao Zhao1,2,3,4, Wenxia Song9, Xuemei Tang1,2,3,4, Zhiyong Zhang1,2,3,4, Xiaodong Zhao1,2,3,4, Chaohong Liu1,2,3,4,7. Dock8 regulates BCR signaling and activation of memory B cells via WASP and CD19. Blood Advances. 2018 Feb 27;2(4):401-413.

 

Jiali Cheng1, Yukai Jing1, Danqing Kang1,LuYang1,Jingwen Li1, ZeYu1, Zican Peng1, Xingbo Li1, Yin Wei2,Quan Gong3,4, Richard J Miron5, Yufeng Zhang5, Chaohong Liu1. The Role of Mst1in Lymphocyte homeostasis and function. Frontiers in Immunology. 2018 Feb 5;9:149. IF=6.429

Li W, Sun X, Wang J, Zhao Q, Dai R, Wang Y, Zhou L, Westerberg L, Ding Y, Zhao X, Liu C. Defective thymic output in WAS patients is associated with abnormal actin organization. Scientific Reports. 2017 Sep 20;7(1):11978. *Co-corresponding author. IF=4.259

Huang L, Zhang Y, Xu C, Gu X, Niu L, Wang J, Sun X, Bai X, Xuan X, Li Q, Shi C, Yu B, Miller H, Yang G, Westerberg LS, Liu W, Song W, Zhao X, Liu C. Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin. PLos Biology. 2017 Aug 18;15(8):e2001750. *Co-corresponding author. IF=9.797

Xiaoming Bai, Lu Huang, Linlin Niu, Yongjie Zhang, Jinzhi Wang, Xiaoyu Sun, Hongyan Jiang, Zhiyong Zhang, Heather Miller, Wufan Tao, Xinyuan Zhou*, Xiaodong Zhao* Chaohong Liu*. Mst1 positively regulates B cell receptor signaling via CD19 transcriptional levels. Blood Advances. 2016 Dec 1(3) 219-230. *Co-corresponding author

Bai X, Zhang Y, Huang L, Wang J, Li W, Niu L, Jiang H, Dai R, Zhou L, Zhang Z, Miller H, Song W, Zhao X, Liu C. The early activation of memory B cells from Wiskott-Aldrich syndrome patients is suppressed by CD19 down regulation. Blood. 2016 Sep 29;128(13):1723-3. *Co-corresponding author. IF=13.164

Zhang X, Dai R, Li W, Zhao H, Zhang Y, Zhou L, Du H, Luo G, Wu J, Niu L, An Y, Zhang Z, Ding Y, Song W, Liu C*, Zhao X*. Abnormalities of follicular helper T-cell number and function in Wiskott-Aldrich syndrome. Blood. 2016 Jun 23;127(25):3180-91. *Co-corresponding author. IF=13.164

 

Liu C*, Richard K, Wiggins M, Zhu X, Conrad DH, Song W*.CD23 can negatively regulate B-cell receptor signaling. Sci Rep. 2016 May 16;6:25629. *Co-corresponding author. IF=4.259

Bai X, Liu J, Zhang Z, Liu C, Zhang Y, Tang W, Dai R, Wu J, Tang X, Zhang Y, Ding Y, Jiang L, Zhao X. Clinical, immunologic, and genetic characteristics of RAG mutations in 15 Chinese patients with SCID and Omenn syndrome. Immunol Res. 2016 Apr;64(2):497-507. IF=3.02

 

Zhang Y, Cheng J, Liu C.The unique role of the hepatitis virus B X protein on HEK 293 cell morphology and cellular change. Arch Virol. 2016 Feb 12. IF=2.39

Qin T, An Y, Liu C, Wu J, Dai R, Liu D, Li X, Jiang L, Wu D, Tang X, Song W, Wang T, Zhao X. Novel DOCK8 gene mutations lead to absence of protein expression in patients with hyper-IgE syndrome. Immunol Res. 2016 Feb;64(1):260-71. IF=3.02


Chaohong Liu, Nicole M. Chapman, Peer Karmaus, Hu Zeng, and Hongbo Chi. mTOR and metabolic regulation of conventional and regulatory T cells. J Leukoc Biol. 2015 Feb 24.IF=4.304

Hongming Miao, Juanjuan Ou, Yinyan Ma, Feng Guo, Zhenggang Yang, Melvin Wiggins, Chaohong Liu, Wenxia Song, Xianlin Han, Miao Wang, Qiang Cao, Houjie Liang, Bingzhong Xue, Hang Shi, Lixia Gan, and Liqing Yu. Macrophage CGI-58 deficiency activates ROS-Inflammasome pathway to promote insulin resistance in mice. Cell Report. 2014 Apr 10;7(1):223-35. IF=7.215  

Chaohong Liu, Xiaoming Bai, Junfeng Wu, Arpita Upadhyaya, Carin I.M. Dahlberg, Lisa. S. Westerberg, Scott B. Snapper, Xiaodong Zhao, Wenxia Song. N-WASP Is Essential for the Negative Regulation of B Cell Receptor Signaling. Plos Biology. 2013 Nov;11(11):e1001704. IF=11.77

 

Chaohong Liu*, Xinwen Chen*. Potential cellular host factor homologous to ZNF-136 can interact with truncated NS2 of HCV. Archive of Virology. 2014 Apr;159(4):785 9.*Corresponding author. IF=2.282

 

Wenxia Song, Chaohong Liu, Margaret K. Seeley-Fallen, Heather Miller, Christina Ketchum, Arpita Upadhyaya. Actin-mediated feedback loops in B-cell receptor signaling. Immunological Reviews. 2013 Nov;256(1):177-89. IF=12.909

 

  Song W, Liu C, Upadhyaya A. The pivotal position of the actin cytoskeleton in the initiation and regulation of B cell receptor activation. Biochim Biophys Acta. 2014 Feb;1838(2):569-78. IF=4.495

Chaohong LIU, Margaret K. FALLEN, Heather MILLER, Arpita UPADHYAYA, Wenxia SONG. The actin cytoskeleton coordinates the signal transduction andantigen processing functions of the B cell antigen receptor. Front. Biol. 2013 Oct;8(5):475-485.

 

Nandini Arunkumar*, Chaohong Liu*, Haiying Hang, and Wenxia Song. Toll-like receptor 9 agonist induces apoptosis in mouse lymphoma B cells by altering NF-kB activation. Cell Mol Immunol. 2013 Jul;10(4):360-72. * Contribute equally. IF=4.185

 

Chaohong Liu*, Yun Wang, Chunchen Wu, Rongjuan Pei, Jianhua Song, Shiyun Chen, Xinwen Chen*. Dioscin's antiviral effect in vitro. Virus Research. 2013 Mar;172(1-2):9-14.* Corresponding author. IF=2.827

 

Liu C*, Miller H, Sharma S, Beaven A, Upadhyaya A, Song W. Analyzing actin dynamics during the activation of the B cell receptor in live B cells. Biochem Biophys Res Commun. 2012 Oct 12; 427(1): 202-6. * Corresponding author. IF=2.281

 

Liu C, Miller H, Orlowski G, Hang H, Upadhyaya A, Song W. Actin reorganization is required for the formation of polarized BCR signalosomes in response to both soluble and membrane-associated antigens. J Immunol. 2012 Apr 1;188(7):3237-46. IF=5.52

 

Becker-Herman S, Meyer-Bahlburg A, Schwartz MA, Jackson SW, Hudkins KL, Liu C, Sather BD, Khim S, Liggitt D, Song W, Silverman GJ, Alpers CE, Rawlings DJ. WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity. J Exp Med. 2011 Sep 26;208(10):2033-42. IF=13.214

Liu C, Miller H, Hui KL, Grooman B, Bolland S, Upadhyaya A, Song W. A balance of Bruton's tyrosine kinase and SHIP activation regulates B cell receptor cluster formation by controlling actin remodeling. J Immunol. 2011 Jul 1;187(1):230-9. IF=5.52

Cao J, Yu JP, Liu CH, Chen XW, Liu S, Luo HS, Yu HG. Effects of hFRNK on E-cadherin/beta-catenin in colon cancer cells in vitro. Zhonghua Zhong Liu Za Zhi. 2007 May;29(5):346-50. Chinese.

Cao Jun,Yu Jieping, Liu Chaohong, et al. Effects of adenovirus vector expression hFRNK on phosphorylated 190RhoGAP and RhoA Activity in colo320WT colorectal cells. Chinese Journal of Practical Internal Medicine; 2007-08.

Jun Cao, Sun Tiehan , Ding Mingyou , Chen Yin, Liu Chaohong , Yu Jieping, Yu Honggang. Construction of inhibiting tumor cell motility and invasion murine FRNK recombinant adenovirus vector. Chinese Journal of Experimental Surgery;2006-12-028.

Cao J, Yu JP, Liu CH, Zhou L, Yu HG. Effects of gastrin 17 on beta-catenin/Tcf-4 pathway in Colo320WT colon cancer cells. World J Gastroenterol. 2006 Dec 14;12(46):7482-7. IF=2.433

Liu Chaohong, Jiao Chensong, Xinwen Chen. Cloning of HCV ns2 gene and its expression in prokaryotic and mammalian cells. Virologica Sinica 2006 21(3):217-220. IF=0.553

 

 

主要承担课题

WASp蛋白为靶向的慢性病和免疫缺陷的治疗  NSFC 8171101261  300万,2018-2020

血液系统的免疫疾病  NSFC 81722002 130万, 2018-2020

CD23调控BCR信号和肌动蛋白重组机制的研究  NSFC 31500709 23万,2015-2018

主要著作

B cell receptor signaling, Methods in Molecular Biology, Springer, 2017



核发:点击数:收藏本页
 官方微信