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药理学系
肖军花

肖军花

e-mail:sosxiao@163.com

个人简介:副教授,硕士导师。2002、2005年分别获华中科技大学硕士、博士学位,2007年至2009年留美做博士后,2012年1月至3月美国加州大学洛杉矶分校访问学者。现主要从事药理学教学和科研。

研究方向:肺纤维化发病机制及药物干预;哮喘气道平滑肌高反应性和重构机制及药物干预;心律失常发病机制及药物干预等。

专著: jun-hua xiao, yong-xiao wang, yun-min zheng. calcium signaling in airway smooth muscle cells (transient receptor potential and orai channels in airway smooth muscle cells), pp35-48, 2014, springer international publishing, doi: 10.1007/978-3-319-01312-1_3, print isbn: 978-3-319-01311-4, online isbn: 978-3-319-01312-1.

代表性论文:

1 wang y, chen ms, liu hc, xiao jh, wang jl. the relationship between frequency dependence of action potential duration and the expression of trpc3 in rabbit ventricular myocardium. cell physiol biochem, 33:646-656, 2014. (通讯作者)

2 chen ms, xiao jh*, wang y, xu bm, gao l, wang jl. upregulation of trpc1 contributes to contractile function in isoproterenol-induced hypertrophic myocardium of rat. cell physiol biochem, 32(4):951-9, 2013. (通讯作者)

3 niu ch, wang y, liu jd, wang jl, xiao jh*. protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice. eur j pharmacol, 714(1-3):112-9, 2013. (通讯作者)

4 zheng ym, park sw, stokes l, tang q, xiao jh, wang yx*. distinct activity of bk channel β1-subunit in cerebral and pulmonary artery smooth muscle cells. am j physiol cell physiol, 304(8):c780-9, 2013.

5 xiao jh, zheng ym, liao b, wang yx. functional role of canonical transient receptor potential 1 and canonical transient receptor potential 3 in normal and asthmatic airway smooth muscle cells. am j respir cell mol biol. 2010 jul;43(1):17-25.

6 xiao jh, zhang yl, feng xl, wang jl, qian jq. effects of isoliensinine on angiotensin ii-induced proliferation of porcine coronary arterial smooth muscle cells. j asian nat prod res. 2006 apr-may; 8(3):209-16.

7 xiao jh, zhang jh, chen hl, feng xl, wang jl. inhibitory effects of isoliensinine on bleomycin-induced pulmonary fibrosis in mice. planta med. 2005 mar; 71(3):225-30.

8 chang mj, xiao jh, wang y, yan yl, yang j, wang jl. 2, 3, 5, 4'-tetrahydroxystilbene-2-o-beta-d-glucoside improves gastrointestinal motility disorders in stz-induced diabetic mice. plos one, 7(12), e50291, 2012

9 zeng c, xiao jh, chang mj, wang jl*. beneficial effects of thsg on acetic acid-induced experimental colitis: involvement of upregulation of ppar-γ and inhibition of the nf-κb inflammatory pathway. molecules, 16, 8552-8568, 2011

10 wan j, zhao l, xu c, zhang s, zhang z, zeng c, chang m, xiao j, wang j*. effects of neferine on the pharmacokinetics of amiodarone in rats. biomed chromatogr, 25, 858–866 2011

11 邓佳慧, 肖军花*, 王嘉陵. 成年小鼠肺成纤维细胞分离纯化及原代培养. 基础医学与临床, 第32卷, 第6期, 713-714, 2012 (通讯作者)

承担的主要科研项目:

国家自然科学基金:调节性t细胞与博莱霉素诱导肺纤维化发病病程及其药物治疗效果的相关性研究

回国留学人员启动基金

华中科技大学创新基金

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