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药理学系
徐旭林

徐旭林,博士,副教授。2004、2009年分别获华中科技大学硕士、博士学位,2007年至2009年在美国弗吉尼亚州立大学做访问学者。现主要从事药理学教学和科研。

主要研究方向:精神神经药理

主持的科研项目:

1.国家自然科学基金:

kcnq2 磷酸化水平调控海马神经元m(kv7)通道活动依赖性转运

代表性论文:

1. xu x, jiang m, wang y, smith t, baumgarten cm, wood ma, tseng gn.long-term fish oil supplementation induces cardiac electrical remodeling by changing channel protein expression in the rabbit model.plos one. 2010 apr 13;5(4):e10140.

3. jiang m, xu x, wang y, toyoda f, liu xs, zhang m, robinson rb, tseng gn.. dynamic partnership between kcnq1 and kcne1 and influence on cardiac iks current amplitude by kcne2. j biol chem. 2009 ;284(24):16452-62.

2. xu x, recanatini m, roberti m, tseng gn. probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (ns1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1h-isoindol-5-ylamino]-nicotinic acid (pd307243). mol. pharmacol. 2008 jun; 73(6):1709-21.

4. xu x, jiang m, hsu kl, zhang m, tseng gn. kcnq1 and kcne1 in the iks channel complex make state-dependent contacts in their extracellular domains. j gen physiol. 2008 jun; 131(6):589-603.

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