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神经生物学系
施静

施静 博士,神经生物学系主任、教授、博士生导师,基础医学院副院长,国家中医药管理局针灸神经生物学3级实验室主任。湖北省神经科学学会理事长,中国神经科学学会理事,《中国组织化学与细胞化学杂志》副主编。主要从事脑缺血神经元保护机制的研究。主持国家自然科学基金2项,教育部博士点基金1项,承担国家自然科学基金重点项目1项,国家攀登计划1项,参与国家自然科学基金5项。在本领域发表学术论文80余篇,近五年以通讯作者发表sci收录论文8篇。曾获湖北省科技进步二等奖、湖北省优秀博士论文奖。所培养的研究生获校优秀博士论文奖和湖北省优秀硕士论文奖。主编《神经生物学实验技术与科学思维》(华中科技大学出版社)及作为副主编主编《医用神经生物学纲要》(科学出版社)、《心血管受体学》(人民卫生出版社),参与编写《神经科学》(第三版)(主编:韩济生)等书。

研究方向:脑缺血神经元保护机制

主要学术论文:

1.yan zeng, xiaohua lv, shaoqun zeng, jing shi*,activity-dependent neuronal control of gap-junctional communication in fibroblasts,brain research,2009,1280,13-22 (通讯作者)

2.yan zeng, xiao-hua l, shao-qun zeng, shun-lian tian, man li, jing shi*, sustained depolarization-induced propagation of [ca2+]i oscillations in cultured drg neurons: the involvement of extracellular atp and p2y receptor activation, brain research,2008,1239,12-23 (通讯作者)

3.hui jiang, shun-lian tian, yan zeng, ling-li li and jing shi*,trka pathway(s) is involved in regulation of trpm7 expression in hippocampal neurons subjected to ischemic- reperfusion and oxygen–glucose deprivation,brain research bulletin, 2008 76 (1):124-130 (通讯作者)

4.li zhao, yue wang, ning sun, xiaochun liu, lingli li, jing shi*, electroacupuncture regulates trpm7 expression through the trka/pi3kpathway after cerebral ischemia–reperfusion in rats, life sciences 81 (2007) 1211–1222 (通讯作者)

5.shun-lian tian, hui jiang, yan zeng, ling-li li, jing shi ?,ngf-induced reduction of an outward-rectifying trpm7-like current in rat ca1 hippocampal neurons , neuroscience letters 419 (2007) 93–98 (通讯作者)

6.yan zeng, jing shi*,electroacupuncture modulates cortical activities evoked by noxious somatosensory stimulations in human brain research, 2006,1097:90-100 (通讯作者)

7.ning sun, xiaojing zou, jing shi*, xiaochun liu, lingli li, li zhao,electroacupuncture regulates nmda receptor nr1 subunit expression via pi3-k pathway in a rat model of cerebral ischemia–reperfusion,brain research, 2005,1064,98–107 (通讯作者)

8.li man, shi j*, et al. effects of complete freund’s adjuvant on immunohistochemical distribution of il-1 and il-1 in neurons and glia cells of dorsal root ganglion, acta pharmacologia sinica, 2005 26(2):192-198 (通讯作者)

主持的科研项目:

1.电针对神经元保护的trka通路与trpm7功能研究(30472234),国家自然科学基金,20,2005.1-2007.12

2.细胞内镁离子激活chak1在缺血神经元迟发性死亡中的作用(30870793),国家自然科学基金,28,2009.1-2011.12

3.经穴信号传导的细胞生物学基础及调控机制研究(90209009),国家自然科学基金重点,100,2005.1-2007.12

4.电针对神经元保护的trka通路与nr1mrna表达的研究,教育部博士点专项基金,6.5,2004.1-2006.12

5.hippocampal-hypothalamic connections and the control of the autonomic balanc(07cdp034)合作:荷兰皇家科学院神经科学研究所,40,2007.9-2010.9

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