武宁

教授，博士生导师

海外高层次人才

华中科技大学同济医学院基础医学院免疫学系

研究方向：免疫信号传导

个人简介：2011年在法国原子能研究所获得博士学位；2011-2017年在加拿大蒙特利尔临床研究所进行博士后研究、ResearchAssociate。2017年9月回国开展独立研究，任华中科技大学同济医学院免疫学系教授。主持和参与多项国家自然科学基金项目（面上3项，参与重点项目1项），科技部重点研发项目子课题负责人（1项）、骨干（1项）。

武宁课题组主要聚焦于细胞质膜特性参与的免疫细胞功能调控与机制的研究。在细胞膜脂非对称性调控、细胞体积大小调控的离子通道（VRAC）参与免疫细胞细胞信号传导与功能调节方面做出原创性发现。在Nature，Nature Immunology, Nature Communications, Science Advances, Advanced Science, Cell Reports, Cell & Mol Immunol等国际权威期刊发表多篇文章。

近年代表性文章：

1. Liu, W., J. Ping, L. Deng, K. Wang, J. Xu, N. Peng, M. Yang, H. Tang, Z. Liu, W. Wang, T. Li, J. Xie, Y. Han, Z. Dong, W. Hu*, Z. Liu*andN. Wu*(2026). "Lipid asymmetry disruption by XKR8 orchestrates neutrophil extracellular trap formation and inhibits fungal infection."Nature Immunology.*Co-corresponding authors

2. Yang, M., Z. Yu, J. Ping, Y. Duan, J. Tang, W. Liu, Q. He, Y. Lai, S. M. Lam, H. Tang, Z. Liu, W. Wang, M. Zhu, W. Hu, Y. Han, G. Shui, J. Hao*, Z. Liu*andN. Wu*(2025). "Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection."Sci Adv11(33): eadx6587.*Co-corresponding authors

3. Tang, J., H. Song, S. Li, S. M.Lam, J. Ping, M. Yang, N. Li, T. Chang, Z. Yu, W. Liu, Y. Lu, M. Zhu, Z. Tang, Z. Liu, Y. R. Guo, G. Shui*, A. Veillette*, Z. Zeng*andN. Wu*(2024)."TMEM16F Expressed in Kupffer Cells Regulates Liver Inflammation and Metabolism to Protect Against Listeria Monocytogenes."Adv Sci(Weinh): e2402693.*Co-corresponding authors

4. Wang, Y., Z. Sun, J. Ping, J. Tang, B. He, T. Chang, Q. Zhou, S. Yuan, Z. Tang, X. Li, Y. Lu, R. He, X. He, Z. Liu*, L. Yin*andWu N.*(2023). "Cell volume controlled by LRRC8A-formed volume-regulated anion channels fine-tunes T cell activation and function."Nat Commun14(1): 7075.*Co-corresponding authors

5. Wu, N.*and A. Veillette*(2023). Lipid scrambling in immunology: why it is important.Cell Mol Immunol: 1-3.#Co-corresponding authors

6. Wu, N.*,#, Song, H.#, and Veillette, A.*(2021). Plasma membrane lipid scrambling causing phosphatidylserine exposure negatively regulates NK cell activation.Cell Mol Immunol. DOI:10.1038/s41423-020-00600-9. #Co-first authors；*Co-corresponding authors

7. Wu, N.*, V.Cernysiov, D. Davidson, H. Song, J. Tang, S. Luo, Y. Lu, J. Qian, I. E. Gyurova, S. N. Waggoner, V. Q. Trinh, R.Cayrol, A. Sugiura, H. M. McBride, J. F. Daudelin, N. Labrecque and A. Veillette*(2020). Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation.Cell Reports30, 1129-1140 e1125.*Co-corresponding authors