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江漫

发布者: [发表时间]:2017-12-14 [来源]: [浏览次数]:

江漫

华中科技大学教授、博士生导师。

联系方式:manjiang@@@hust.edu.cn(去掉两个@)



个人简历

2012年在中国科学院神经科学研究所获博士学位。2013年至2018年初在美国斯坦福大学从事博士后研究,师从诺奖得主Thomas C. Südhof教授,主要研究突触粘附分子与神经环路的发育。已在Neuron,Molecular Psychiatry,Science Advances, Biological Psychiatry,eLife, PLoS Biology,Cerebral Cortex等期刊发表多篇高质量研究论文。2018年1月入职生理系。



主要研究方向

1)突触粘附分子调节突触功能和动物行为的机制;

2)突触功能异常导致神经发育障碍的机制;

3)小鼠社交行为的神经环路机制。



代表性论文

  1. Zijiao Ding#, Guiyang Huang#, Tianyun Wang#, Weicheng Duan, Hua Li, Yirong Wang, Huiting Jia, Ziqian Yang, Kang Wang, Xufeng Chu, Evangeline C Kurtz-Nelson, Kaitlyn Ahlers, Rachel K Earl, Yunyun Han, Pamela Feliciano, Wendy K Chung, Evan E Eichler,Man Jiang*, Bo Xiong*. (2023). Genetic ablation of GIGYF1, associated with autism, causes behavioral and neurodevelopmental defects in zebrafish and mice.Biological Psychiatry.doi: https://doi.org/10.1016/j.biopsych.2023.02.993(*co-corresponding author).

  2. Pei-Yi Lin#, Lulu Y. Chen#,Man Jiang#, Justin H. Trotter, Erica Seigneur, and Thomas C. Südhof. (2023). Neurexin-2: An Inhibitory Neurexin That Restricts Excitatory Synapse Formation in the Hippocampus.Science Advances. doi: 10.1126/sciadv.add8856(#co-first author)

  3. Jun Zhou#, Wen Deng#, Chen Chen, Junya Kang, Xiaodan Yang, Zhaojuan Dou, Jiancheng Wu, Quancong Li,Man Jiang*, Man Liang*, Yunyun Han*. (2022). Methcathinone increases visually evoked neuronal activity and enhances sensory processing efficiency in mice.Neuroscience Bulletin. doi: 10.1007/s12264-022-00965-z(*co-corresponding author).

  4. Zhihui Liu*,Man Jiang, Kif Liakath-Ali, Alessandra Sclip, Jaewon Ko, Roger Shen Zhang, Thomas C Südhof*. (2022). Deletion of Calsyntenin-3, an atypical cadherin, suppresses inhibitory synapses but increases excitatory parallel-fiber synapses in cerebellum.eLife11: e70664. doi:10.7554/eLife.70664

  5. Susu Pan, Kaili Yin, Zhiwei Tang, Shuren Wang, Zhuo Chen,Yirong Wang, Hongxia Zhu, Yunyun Han, Mei Liu*,Man Jiang*, Ningzhi Xu*, Guo Zhang*. (2021). Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice.eLife10:e67535.doi:10.7554/eLife.67535 (*co-corresponding author).

  6. Man Jiang#, Jai S. Polepalli#, Lulu Y. Chen, Bo Zhang, Thomas C. Südhof, Robert C. Malenka. (2017). Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism.Molecular Psychiatry22, 375–383; doi:10.1038/mp.2016.80 (#co-first author).

  7. Lulu Y. Chen#,Man Jiang#, Bo Zhang, Ozgun Gokce, and Thomas C. Südhof (2017). Conditional Deletion of All Neurexins DefinesDiversity of Essential Synaptic Organizer Functionsfor Neurexins.Neuron94(3): 611–625; doi: 10.1016/j.neuron.2017.04.011 (#co-first author)

  8. Man Jiang, Mingpo Yang, Luping Yin, Xiaohui Zhang and Yousheng Shu. (2015) Developmental Reduction of Asynchronous GABA Release from Neocortical Fast-Spiking Neurons.Cerebral Cortex. 25 (1): 258-270; doi: 0.1093/cercor/bht236.

  9. Man Jiang, Jie Zhu, Yaping Liu, Mingpo Yang, Cuiping Tian, Shan Jiang, Yonghong Wang, Hui Guo, Kaiyan Wang&Yousheng Shu (2012). Enhancement of Asynchronous Release from Fast-Spiking Interneuron in Human and Rat Epileptic Neocortex.PLoS Biology10(5): e1001324.

  10. Fujun Luo, Alessandra Sclip,Man Jiang, Thomas C Südhof (2020). Neurexins cluster Ca2+channels within the presynaptic active zone. EMBO J, 2020, 39(7): e103208. doi: 10.15252/embj.2019103208

  11. Suixin Deng, Junlong Li, Quansheng He, Xiaoxue Zhang, Jie Zhu, Liang Li, Zhen Mi, Xiufeng Yang,Man Jiang, Qiang Dong, Ying Mao, Yousheng Shu (2017). Regulation of Recurrent Inhibition by Asynchronous Glutamate Release in Neocortex.Neuron105(3):522-533.e4. doi: 10.1016/j.neuron.2019.10.038

  12. Wei Yue, Yuanyuan Li, Ting Zhang,Man Jiang, Yun Qian, Min Zhang, Nengyin Sheng, Su Feng, Ke Tang, Xiang Yu, Yousheng Shu, Chunmei Yue, Naihe Jing. (2015) ESC-Derived Basal Forebrain Cholinergic Neurons Ameliorate the Cognitive Symptoms Associated with Alzheimer’s Disease in Mouse Models.Stem Cell Reports.5(5):776–790;doi: 10.1016/j.stemcr.2015.09.010

  13. Jie Zhu,Man Jiang, Mingpo Yang, Han Hou, and Yousheng Shu.(2011) Membrane Potential-Dependent Modulation of Recurrent Inhibition in Rat Neocortex.PLoS Biology9(3): e1001032.